金沙国际电玩城

分子生物学教研室

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袁猛

来源: 责任编辑: 发布:2015-11-04 点击量:


袁猛博士 教授 博士生导师

国家自然科学基金委优秀青年科学基金获得者

国家自然科学基金委“绿色超级稻生物学”创新群体核心成员

教育经历

1999-2003金沙电子游戏网址大全 园艺林学学院 林学专业 农学学士学位

2003-2010金沙电子游戏网址大全 金沙国际电玩城 生物化学与分子生物学专业 理学博士学位

科研与学术工作经历

2011.01-2012.12金沙国际电玩城 讲师

2013.01-2018.08金沙国际电玩城 副教授

2016.11-2017.12美国杜克大学 访问学者

2018.09-至今 金沙国际电玩城 教授

2011.01-至今 作物遗传改良国家重点实验室固定研究人员

研究方向

整合遗传学、生物化学、分子生物学、生物信息学和分子植物病理学的知识和技术,开展水稻抗病基因挖掘、功能和调控机制研究工作。

代表性研究成果

论文

1.Cao J, Chu C, Zhang M, He L, Qin L, Li X,Yuan M(2020) Different cell wall-degradation ability leads to tissue-specificity betweenXanthomonas oryzaepv.oryzaeandXanthomonas oryzaepv.oryzicola. Pathogens. 9:187.

2.Ke Y,Yuan M, Liu H, Hui S, Qin X, Chen J, Zhang Q, Li X, Xiao J, Zhang Q, Wang S (2020) The versatile functions of OsALDH2B1 provide a genic basis for growth-defense trade-offs in rice. Proc Natl Acad Sci USA. 117:3867-3873.

3.Yoo H#, Greene GH#,Yuan M#, Xu G, Burton D, Liu L,MarquésJ, Dong X (2020) Translational regulation of metabolic dynamics during effector-triggered immunity. Mol Plant. 13:88-98. (co-first author)

4.Cao J, Zhang M, Zhu M, He L, Xiao J, Li X,Yuan M(2020) Autophagy-like cell death regulates hydrogen peroxide and calcium ion distribution inXa3/Xa26-mediated resistance toXanthomonas oryzaepv.oryzae. Int J Mol Sci. 21:194.

5.Tian J, Xu G,Yuan M(2019) Precise editing enables crop broad-spectrum resistance. Mol Plant. 12:1542-1544.

6.Zhang M, Wang S,Yuan M(2019) An update on molecular mechanism of disease resistance genes and their application for genetic improvement of rice. Mol Breeding. 39: 154.

7.Hui S, Liu H, Zhang M, Chen D, Li Q, Tian J, Xiao J, Li X, Wang S,Yuan M(2019) The host basal transcription factor IIA subunits coordinate for facilitating infection of TALEs-carrying bacterial pathogens in rice. Plant Sci. 284: 48-56.

8.Hui S, Shi Y, Tian J, Wang L, Li Y, Wang S,Yuan M(2019) TALE-carrying bacterial pathogens trap host nuclear import receptors for facilitating infection of rice. Mol Plant Pathol. 20: 519-532.

9.Huang R, Li Y, Tang G, Hui S, Yang Z, Zhao J, Liu H, Cao J,Yuan M(2018) Dynamic phytohormone profiling of rice uponrice black-streaked dwarf virusinvasion. J Plant Physiol. 228: 92-100.

10.Xu G#,Yuan M#, Ai C, Liu L, Zhuang E, Karapetyan S, Wang S, Dong X (2017) uORF-mediated translation allows engineered plant disease resistance without fitness costs. Nature. 545: 491-494. (co-first author)

11.Huang R, Hui S, Zhang M, Li P, Xiao J, Li X,Yuan M, Wang S (2017) A conserved basal transcription factor is required for the function of diverse TAL effectors in multiple plant hosts. Front Plant Sci. 8: 1919.

12.Ke Y, Hui S,Yuan M(2017)Xanthomonas oryzaepv.oryzaeinoculation and growth rate on rice by leaf clipping method. Bio-protocol. 7: e2568.

13.Yuan M, Ke Y, Huang R, Ma L, Yang Z, Chu Z, Xiao J, Li X, Wang S (2016) A host basal transcription factor is a key component for infection of rice by TALE-carrying bacteria. Elife. 5: e19605. (co-corresponding author).

14.Su J, Zou X, Huang J, Bai T, Liu S,Yuan M, Chou SH, He YW, Wang H, He J (2016) DgcA, a diguanylate cyclase fromXanthomonas oryzaepv.oryzaeregulates bacterial pathogenicity on rice. Sci Rep. 6: 25978.

15.Xie W, Wang G,Yuan M, Yao W, Lyu K, Zhao H, Yang M, Li P, Zhang X, Yuan J, Wang Q, Liu F, Dong H, Zhang L, Li X, Meng X, Zhang W, Xiong L, He Y, Wang S, Yu S, Xu C, Luo J, Li X, Xiao J, Lian X, Zhang Q (2015) Breeding signatures of rice improvement revealed by a genomic variation map from a large germplasm collection. Proc Natl Acad Sci USA. 112: E5411-9.

16.Yuan M, Zhao J, Huang R, Li X, Xiao J, Wang S (2014) Rice MtN3/saliva/SWEET gene family: evolution, expression profiling, and sugar transport. J Integr Plant Biol. 56: 559-570.

17.Zhou Y, Liu L, Huang W,Yuan M, Zhou F, Li X, Lin Y (2014) Overexpression of OsSWEET5 in rice causes growth retardation and precocious senescence. PLoS One. 9: e94210.

18.Yuan M, Wang S (2013) Rice MtN3/Saliva/SWEET family genes and their homologues in cellular organisms. Mol Plant. 6: 665-674.

19.Liu Q,Yuan M, Zhou Y, Li X, Xiao J, Wang S (2011) A paralog of the MtN3/saliva family recessively confers race-specific resistance toXanthomonas oryzaein rice. Plant Cell Environ. 34: 1958-1969.

20.Yuan M, Li X, Xiao J, Wang S (2011) Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biology. 11: 69.

21.Yuan M, Chu Z, Li X, Xu C, Wang S (2010) The bacterial pathogenXanthomonas oryzaeovercomes rice defenses by regulating host copper redistribution. Plant Cell 22: 3164-3176.

22.Yuan M, Chu Z, Li X, Xu C, Wang S (2009) Pathogen-induced expressional loss of function is the key factor in race-specific bacterial resistance conferred by a recessive R genexa13inrice. Plant Cell Physiol. 50: 947-955.

23.Chu Z,Yuan M, Yao J, Ge X, Yuan B, Xu C, Li X, Fu B, Li Z, Bennetzen JL, Zhang Q, Wang S (2006) Promoter mutations of an essential gene for pollen development result in disease resistance in rice. Genes Dev. 20: 1250-1255.

24.Wang G, Ding X,Yuan M, Qiu D, Li X, Xu C, Wang S (2006) Dual function of rice OsDR8 gene in disease resistance and thiamine accumulation. Plant Mol Biol. 60: 437-449.

授权专利

ZL201010595883.7,ZL200910063141.7,ZL200910063051.8,ZL200510018674.5。

主讲课程

分子克隆技术、生物信息学(国家精品资源共享课、MOOC)

研究生招生专业

生物化学与分子生物学

联系方式

实验室电话:027-87281812

电子邮箱:myuan@mail.hzau.edu.cn

办公地点:作物遗传改良国家重点实验室A508

实验室介绍及网址:

基因组研究与水稻遗传改良团队抗病课题组


中国·湖北·武汉 南湖狮子山街一号430070 Tel:+86-27-87282101 E-mail:bio@mail.hzau.edu.cn

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